Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 38
Release date: Jul 1 2011
Last update date: Mar 23 2012
Access: Public
Diseases: Breast Neoplasms, Neoplasms
Chemicals: Estrogens
Dataset link Differentially expressed genes in window trials are influenced by the wound healing process: lessons learned from a pilot study with Anastrozole

Experimental Protocol


Prospective, paired tumor samples (biopsy and surgical) were obtained from 26 postmenopausal women with ER-positive breast cancer. Patients were assigned anastrozole (1mg/dy) for 10 days immediately prior to surgery (13 cases) or no treatment (13 controls). 502 cancer-related genes were examined by the DASL FFPE-based cDNA array. Sufficient RNA for gene expression analysis was obtained from 19/26 (73%) FFPE paired (biopsy and surgery) samples (8 controls, 11 anastrozole-treated patients

Repositories


GEO

GSE26544

ArrayExpress

E-GEOD-26544

BioProject

PRJNA136623

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Contact


Victor Andrade
Victor Piana Andrade