Dataset features

Specifications


Application: Gene expression microarray analysis, miRNA array analysis
Number of samples: 8
Release date: Jun 9 2012
Last update date: May 2 2017
Access: Public
Diseases: Breast Neoplasms, Leukemia, Neoplasms
Dataset link MicroRNA expression data from leukemia and breast cancer cell lines with/without treatment with microparticles

Experimental Protocol


Total RNA was extracted and pooled from duplicate experiments for hybridization on Affymetrix microarrays from (i) the parental drug sensitive leukaemia (CEM) or breast cancer (MCF-7) cells, (ii) their Multidrug Resistant strains leukaemia (VLB100) or breast cancer ( DX cells), (iii) the microparticles isolated from the resistant cells: VLBMP or DXMP, and (iv) the cocultured samples: sensitive cell co-incubated with MPs from their resistant cells ( leukaemia: CEM+VLBMP) or(breast cancer: MCF-7+DXMP). We sought to examine the miRNA profiles of the drug sensitve cells after MP transfer from drug resistant cells across leukaemia nd breact cancer cell lines.

Repositories


GEO

GSE34560

ArrayExpress

E-GEOD-34560

BioProject

PRJNA151529

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Contact


Ritu Jaiswal