|Application:||Gene expression microarray analysis, miRNA array analysis|
|Number of samples:||8|
|Release date:||Jun 9 2012|
|Last update date:||May 2 2017|
|Diseases:||Breast Neoplasms, Leukemia, Neoplasms|
|Dataset link||MicroRNA expression data from leukemia and breast cancer cell lines with/without treatment with microparticles|
Total RNA was extracted and pooled from duplicate experiments for hybridization on Affymetrix microarrays from (i) the parental drug sensitive leukaemia (CEM) or breast cancer (MCF-7) cells, (ii) their Multidrug Resistant strains leukaemia (VLB100) or breast cancer ( DX cells), (iii) the microparticles isolated from the resistant cells: VLBMP or DXMP, and (iv) the cocultured samples: sensitive cell co-incubated with MPs from their resistant cells ( leukaemia: CEM+VLBMP) or(breast cancer: MCF-7+DXMP). We sought to examine the miRNA profiles of the drug sensitve cells after MP transfer from drug resistant cells across leukaemia nd breact cancer cell lines.