Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 30
Release date: Jan 26 2016
Last update date: Nov 1 2017
Access: Public
Dataset link Cortex PS2 APP transgenic mice

Experimental Protocol


5 Male transgenic and 5 Male wild-type mice were perfused and sacrificed at 3 months (earliest behavioral changes), 7 months (inflammation and plaque pathology), or 13 months (spreading synapse loss) of age. Hemicortices were subdissected and flash frozen prior to RNA extraction using the RNeasy Lipid Tissue extraction kit with on-column Dnase digestion.

Repositories


GEO

GSE74995

BioProject

PRJNA302153

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Contact


Brad Friedman

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