Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 24
Release date: Oct 12 2016
Last update date: Jan 11 2017
Access: Public
Diseases: Ductus Arteriosus, Patent, Heart Defects, Congenital
Chemicals: Ibuprofen, Indomethacin
Dataset link Microarray gene expression analysis in ovine ductus arteriosus during fetal development and birth transition.

Experimental Protocol


We isolated DA and a segment of ascending aorta from preterm (97±0 days gestation) and near-term (136 ± 0.8 days) fetal sheep (full term = 145 days) and from 12±0 hours old newborn lambs (obtained from Pozzi Ranch, Valley Ford, CA)). Four animals (n=4) were used for each experimental group. At the time of experimental study, ewes and newborn lambs were euthanized with an overdose of the proprietary euthanasia solution Euthasol (pentobarbital sodium 100 mg.Kg-1 and phenytoin sodium 10 mg.Kg-1; Virbac, Ft. Worth, TX).

Repositories


GEO

GSE87840

BioProject

PRJNA347841

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Contact


Ravi Goyal