|Application:||Gene expression microarray analysis|
|Number of samples:||28|
|Release date:||Oct 1 2010|
|Last update date:||Aug 23 2018|
|Chemicals:||Acetaldehyde, Ethanol, Glutathione|
|Dataset link||Hepatic xenobiotic metabolizing enzyme gene expression through the life stages of the mouse|
We characterized gene expression changes in the developing mouse liver at gestational days (GD) 19), neonatal (postnatal day (PND) 7), prepubescent (PND30), middle age (12 mon), and old age (18 and 24 mon) in the C57Bl6/J mouse liver using full-genome microarrays and compared these changes to that in the adult liver.. We also compared results to GD19, PND32, and PND67 C3H mice. Total RNA was isolated from liver samples and gene expression analyzed using Affymetrix Mouse 430 2.0 GeneChips. Data from 28 samples, four mice in each of the age groups for C57BL/6 and C3H, were analyzed.