Computational protocol: C-element: A New Clustering Algorithm to Find High Quality Functional Modules in PPI Networks

Similar protocols

Protocol publication

[…] The proposed algorithm consists of two main parts. The main goal of the first part is to find the best seeds by finding and removing the special proteins that might belong to the several clusters and consequently to find the best clusters. We expect that the result of this part outperforms the results of the seed-based algorithms such as SPICi and clusterOne. The main idea of the second part is to take also the profits of clique based clustering algorithms as a complementary solution. In the rest of this section, we explain each part in more detail. shows an overview of the proposed algorithm. […]

Pipeline specifications

Software tools SPICi, ClusterONE
Application Protein interaction analysis
Organisms Caenorhabditis elegans, Homo sapiens