Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 16
Release date: Oct 15 2016
Last update date: Aug 23 2018
Access: Public
Diseases: Carcinoma, Carcinoma, Squamous Cell, Neoplasms
Dataset link Cell type-specific chromatin states differentially prime squamous cell carcinoma tumor-initiating cells for epithelial to mesenchymal transition [expression 1]

Experimental Protocol


KrasG12D and YFP expression combined with deletion of p53 were induced in Hair Follicle Stem cells (SCs) and their progeny using Lgr5CREER/KRasG12D/p53fl/fl/Rosa-YFP mice, and in the Intra Follicular Epidermis and the infundibulum using K14CREER/KRasG12D/p53fl/fl/Rosa-YFP mice by intraperitoneal tamoxifen injection. Cells were harvested and compared prior oncogenic hits and in fully grown tumours.

Repositories


GEO

GSE87877

BioProject

PRJNA348518

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Contact


C├ędric Blanpain