Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 104
Release date: Apr 26 2012
Last update date: Jul 8 2016
Access: Public
Diseases: Lupus Erythematosus, Systemic, Epstein-Barr Virus Infections
Dataset link Evidence of Dynamically Dysregulated Gene Expression Pathways in Hyper-responsive B Cells from African American Lupus Patients

Experimental Protocol


Epstein-Barr virus (EBV) transformed B cells derived from two patients with systemic lupus erythematosus (SLE) and two normal unrelated controls were stimulated with a biologically relevant signal, co-crosslinking of the B cell antigen receptor (BCR) and FcγR2b. Total RNA was isolated at various timepoints post-stimulation. Gene expression data were used for analysis of differential gene expression and analysis of the dynamics of gene expression variations.

Repositories


GEO

GSE37573

ArrayExpress

E-GEOD-37573

BioProject

PRJNA162303

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Contact


Igor Dozmorov