|Application:||Gene expression microarray analysis|
|Number of samples:||6|
|Release date:||Dec 19 2012|
|Last update date:||Apr 5 2017|
|Diseases:||Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms|
|Dataset link||PIAS3 induction of apoptosis in non-small cell lung cancer cells is p53-independent and has STAT3-independent mediator.|
The expression profiles of genes related to apoptosis in A549 cell line transfected with pCMV5 vector encoding human PIAS3 compared with that induced by STAT3 siRNA Cells in all three groups were grown in serum-free medium, then stimulated with EGF, then one group transfected with pCMV5 vector encoding human PIAS3, second group was induced by STAT3 siRNA, third group considered as control.