Computational protocol: A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5α

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Protocol publication

[…] The structure of the N-terminal domain of the HIV-1 CA protein (PDB number 1GWP) [] was used as a template for building the domain model with the G116E substitution. The model was built using Modeller 9v4 [] and visualized with PyMOL v1.0r2 (The PyMOL Molecular Graphics System, http://pymol.sourceforge.net/). […]

Pipeline specifications

Software tools MODELLER, PyMOL
Application Protein structure analysis
Organisms Human immunodeficiency virus 1, Homo sapiens, Pan troglodytes
Diseases Acquired Immunodeficiency Syndrome, HIV Infections
Chemicals Amino Acids