Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 31
Release date: Aug 29 2012
Last update date: Jan 17 2013
Access: Public
Diseases: Neoplasms, Prostatic Neoplasms
Chemicals: Mitoxantrone
Dataset link Molecular alterations in prostate carcinomas that associate with in vivo exposure to chemotherapy

Experimental Protocol


To evaluate gene expression alterations after chemotherapy, neoplastic epithelium from pretreated biopsy and posttreated prostatectomy specimens were laser captured separately (∼3,000 cells per sample). cDNA synthesized from amplified total RNA of pre-treated biopsy samples and post-treatment surgical samples were hybridized head-to-head, alternating Cy3 and Cy5 to custom-made microarrays composed of 6,200 clones derived from the Prostate Expression Database.

Repositories


GEO

GSE40434

ArrayExpress

E-GEOD-40434

BioProject

PRJNA174035

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Contact


Ilsa Coleman