Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 14
Release date: Dec 1 2016
Last update date: Jun 14 2018
Access: Public
Taxon: Mus musculus
Dataset link Host response in murine fecal peritonitis differs upon the specific fecal microbiota

Experimental Protocol


Sepsis can be induced in mice by injecting stool in peritoneal cavity of mice. These models are also known as Peritoneal Contamination and Infection (PCI) models. Heterologous samples were used to understand septic response after injecting fecal slurry from human. Homologous samples were used to understand septic response after injecting fecal slurry from mouse. [blood_het] RNA from murine circulating leukocytes from whole blood (n=4 for sepsis) was extracted and subjected to microarray analysis for comparison of transcriptomic responses. [blood_hom] RNA from murine circulating leukocytes from whole blood (n=3 for sepsis) was extracted and subjected to microarray analysis for comparison of transcriptomic responses. [liver_het] RNA from liver tissue (n=4 for sepsis) was extracted and subjected to microarray analysis for comparison of transcriptomic responses. [liver_hom] RNA from liver tissue (n=3 for sepsis) was extracted and subjected to microarray analysis for comparison of transcriptomic responses.

Repositories


GEO

GSE70714

BioProject

PRJNA289440

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Contact


Falk Gonnert