|Application:||Gene expression microarray analysis|
|Number of samples:||8|
|Release date:||Mar 31 2010|
|Last update date:||Aug 28 2018|
|Dataset link||Visualization of cancer initiating cell in the vascular niche utilized with transcriptional activity of PSF1|
We have cloned the mouse PSF1 promoter gene and established lung carcinoma (lewis lung carcinoma: LLC) and colon cancer (colon26) cell lines stably expressing enhanced green fluorescent protein (EGFP) under the transcriptional control of PSF1 promoter (LLC- and colon-PSF1P-EGFP, respectively). Mouse xenograft tumor cells were dissociated and sorted into PSF1 low and high expression cells by FACS. We sought whether PSF1 high expression cells possess embryonic stem cells-like signature.