Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 32
Release date: Oct 24 2005
Last update date: Aug 23 2018
Access: Public
Diseases: Hypoxia
Chemicals: Oxygen
Dataset link Two transactivation mechanisms are responsible for the bulk of HIF-1alpha-responsive gene expression

Experimental Protocol


Three separate affymetrix experiments using mouse embryonic fibroblasts derived from embryos bearing the ?CH1 mutation in p300 and/or CBP and treated with hypoxia or combinations of dipyridyl (a hypoxia mimetic) and trichostatin A (a histone deacetylase inhibitor) are described (GSE3195, GSE3196 and GSE3296). Samples are not directly comparable between experiments because of differences in experiment design and Affymetrix chips used.

Repositories


GEO

GSE3318

ArrayExpress

E-GEOD-3318

BioProject

PRJNA93353

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Contact


Paul Brindle
Paul K. Brindle