|Application:||Gene expression microarray analysis|
|Number of samples:||32|
|Release date:||Oct 24 2005|
|Last update date:||Aug 23 2018|
|Dataset link||Two transactivation mechanisms are responsible for the bulk of HIF-1alpha-responsive gene expression|
Three separate affymetrix experiments using mouse embryonic fibroblasts derived from embryos bearing the ?CH1 mutation in p300 and/or CBP and treated with hypoxia or combinations of dipyridyl (a hypoxia mimetic) and trichostatin A (a histone deacetylase inhibitor) are described (GSE3195, GSE3196 and GSE3296). Samples are not directly comparable between experiments because of differences in experiment design and Affymetrix chips used.
Paul K. Brindle