|Application:||Gene expression microarray analysis|
|Number of samples:||41|
|Release date:||Jan 1 2018|
|Last update date:||Apr 2 2018|
|Dataset link||Bone healing in an aged murine fracture model is characterized by sustained callus inflammation and decreased cell proliferation|
Mice aged 5 months “young” or 25 months “geriatric” underwent bilateral tibial fractures and fracture calluses were harvested at 0, 5, 10, and 20 days post fracture (DPF) for analysis, yielding a total of 41 samples. For each time point and DPF, a group of 5 to 6 unique mice were harvested. Global gene expression analysis was performed using Affymetrix MoGene 1.0 ST microarrays. After normalization, data were compared using ANOVA and evaluated using Principal Component Analysis (PCA), CTen, heatmap, and Incromaps analysis.