Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 41
Release date: Jan 1 2018
Last update date: Apr 2 2018
Access: Public
Diseases: Tooth Fractures
Dataset link Bone healing in an aged murine fracture model is characterized by sustained callus inflammation and decreased cell proliferation

Experimental Protocol


Mice aged 5 months “young” or 25 months “geriatric” underwent bilateral tibial fractures and fracture calluses were harvested at 0, 5, 10, and 20 days post fracture (DPF) for analysis, yielding a total of 41 samples. For each time point and DPF, a group of 5 to 6 unique mice were harvested. Global gene expression analysis was performed using Affymetrix MoGene 1.0 ST microarrays. After normalization, data were compared using ANOVA and evaluated using Principal Component Analysis (PCA), CTen, heatmap, and Incromaps analysis.

Repositories


GEO

GSE99388

BioProject

PRJNA388355

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