Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 8
Release date: Jun 15 2016
Last update date: Jun 15 2016
Access: Public
Diseases: Neoplasms, Neoplasms, Second Primary, Alcohol-Induced Disorders, Precursor Cell Lymphoblastic Leukemia-Lymphoma
Genes: NCX, TAS1R1, NR2C1, TNFRSF25, CFLAR, BIRC5, TNFRSF10A, TNFRSF10B
Dataset link Acquired resistance of Jurkat cells to TNF-related apoptosis-inducing ligand (TRAIL): a role for histone deacetylase inhibitors as powerful apoptosis sensitizer.

Experimental Protocol


Total cellular RNA was isolated from biologic duplicates of untreated Jurkat cells (WT), TRAIL resistant Jurkat cell clone (TR1) and 1 µM and 0.5 µM suberoylanilide-hydroxamic acid (SAHA, vorinostat) treated TR1 cell clones for 12 hours. Jurkat cell line subclones TR1was established by selective pressure of TRAIL 1000 ng/mL on Jurkat cells over the period of 12 weeks.

Repositories


GEO

GSE38745

ArrayExpress

E-GEOD-38745

BioProject

PRJNA168558

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