|Application:||Gene expression microarray analysis|
|Number of samples:||8|
|Release date:||Jun 15 2016|
|Last update date:||Jun 15 2016|
|Diseases:||Neoplasms, Neoplasms, Second Primary, Alcohol-Induced Disorders, Precursor Cell Lymphoblastic Leukemia-Lymphoma|
|Genes:||NCX, TAS1R1, NR2C1, TNFRSF25, CFLAR, BIRC5, TNFRSF10A, TNFRSF10B|
|Dataset link||Acquired resistance of Jurkat cells to TNF-related apoptosis-inducing ligand (TRAIL): a role for histone deacetylase inhibitors as powerful apoptosis sensitizer.|
Total cellular RNA was isolated from biologic duplicates of untreated Jurkat cells (WT), TRAIL resistant Jurkat cell clone (TR1) and 1 µM and 0.5 µM suberoylanilide-hydroxamic acid (SAHA, vorinostat) treated TR1 cell clones for 12 hours. Jurkat cell line subclones TR1was established by selective pressure of TRAIL 1000 ng/mL on Jurkat cells over the period of 12 weeks.