|Application:||Gene expression microarray analysis, miRNA array analysis|
|Number of samples:||24|
|Release date:||Mar 8 2010|
|Last update date:||Jan 30 2018|
|Diseases:||Heart Failure, Myocardial Infarction|
|Dataset link||microRNA profiling of myocardial infarction on a PI3K setting in mouse models|
Ntg (non-transgenics), dnPI3K (cardiac-specific transgenic model with reduced PI3K activity) and caPI3K (transgenic mice with increased PI3K activity) mice at 3-4 months of age were used. Mice were then subjected to myocardial infarction (occlusion of the left anterior descending aorta) and sham (open heart surgery) for 8 weeks. Left ventricles were harvested. The resulting 6 experimental models were profiled accordingly. The assignment of the mouse models is as follows: caPI3K Sham, Ntg Sham, dnPI3K Sham, caPI3K MI (myocardial infarction), Ntg MI and dnPI3K MI with n = 4 in each group.
Ruby CY Lin