Dataset features

Specifications


Application: Gene expression microarray analysis, miRNA array analysis
Number of samples: 24
Release date: Mar 8 2010
Last update date: Jan 30 2018
Access: Public
Diseases: Heart Failure, Myocardial Infarction
Dataset link microRNA profiling of myocardial infarction on a PI3K setting in mouse models

Experimental Protocol


Ntg (non-transgenics), dnPI3K (cardiac-specific transgenic model with reduced PI3K activity) and caPI3K (transgenic mice with increased PI3K activity) mice at 3-4 months of age were used. Mice were then subjected to myocardial infarction (occlusion of the left anterior descending aorta) and sham (open heart surgery) for 8 weeks. Left ventricles were harvested. The resulting 6 experimental models were profiled accordingly. The assignment of the mouse models is as follows: caPI3K Sham, Ntg Sham, dnPI3K Sham, caPI3K MI (myocardial infarction), Ntg MI and dnPI3K MI with n = 4 in each group.

Repositories


GEO

GSE14267

ArrayExpress

E-GEOD-14267

BioProject

PRJNA111229

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Contact


Ruby Lin
Ruby CY Lin