Computational protocol: Prognostic significance of ALCAM (CD166/MEMD) expression in cutaneous melanoma patients

Similar protocols

Protocol publication

[…] Statistical analysis was performed using the Statistica 10.0 and IBM SPSS 21 software packages. Overall survival (OS) was defined as the time between the primary surgical treatment and death, and OS was censored at last follow-up for patients who were still alive. Disease-free survival (DFS) was defined as the time between the primary surgical treatment and the date of relapse. DFS was censored at the last follow-up for patients who survived without disease recurrence or at the date of non-cancer associated death. Cancer-specific overall survival (CSOS) was defined as the time between the primary surgical treatment and cancer-associated death, and was censored at the last follow-up for surviving patients.A χ2 test, exact Fisher test in the case of 2 × 2 tables, and Spearman rank correlation were used to analyze associations between mitotic rate and the presence of ulceration and clinicopathological parameters. Differences between the means were tested with a nonparametric test (Mann–Whitney U test and Kruskal-Wallis test), the log-rank test was used to compare survival in two groups, the overall survival rate was estimated by the Kaplan-Meier method and the influence of explanatory variables on death risk was analyzed by means of the Cox proportional hazard regression. P values <0.05 were considered statistically significant. […]

Pipeline specifications

Software tools Statistica, SPSS
Application Miscellaneous
Organisms Homo sapiens
Diseases Melanoma, Neoplasms