Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 63
Release date: Sep 17 2018
Last update date: Sep 17 2018
Access: Public
Diseases: Mevalonate Kinase Deficiency, Hereditary Autoinflammatory Diseases
Chemicals: Steroids
Dataset link Canakinumab treatment in hyperimmunoglobulinemia D with periodic fever syndrome

Experimental Protocol


63 samples total. 7 at visit 1: anakinra treatment (V1_AK) 9 at visit 2: during active disease after anakinra withdrawal (V2_NT) 9 at visit 3: after anakinra withdrawal and on canakinumab (V3) 8 at visit 4: after anakinra withdrawal and on canakinumab (V4) 8 at visit 5: after anakinra withdrawal and on canakinumab (V5) 15 age- and sex-matched healthy controls (HC). Note: V2_NT is BL in the associated manuscript. 7 at visit 6: during active disease after canakinumab withdrawal (ATTACK)

Repositories


GEO

GSE97075

BioProject

PRJNA380632

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