Computational protocol: Rb is required for retinal angiogenesis and lamination

Similar protocols

Protocol publication

[…] The dataset GSE86372 at NCBI GEO database (http://www.ncbi.nlm.nih.gov/geo/) was used to compare WT vs. RbKO mouse P8 retinas, which include three WT and three RbKO mouse P8 retinas. The data were analyzed by GEO2R from the GEO website. The genes, of which expression fold changes are >2 or <0.5, and adjusted p < 0.05 were selected as the RbKO-related DEGs. Totally 677 DEGs were identified. The heatmap was generated using Heatmapper. The function enrichment of DEG was performed using Enrichr,, the pathways with adjusted p < 0.05 were chosen to report. […]

Pipeline specifications

Software tools GEO2R, Heatmapper, Enrichr
Applications Transcription analysis, Transcriptome data visualization
Organisms Mus musculus, unidentified adenovirus