Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 9
Release date: Jan 1 2016
Last update date: Aug 22 2018
Access: Public
Dataset link Gene expression profile in CD4+ T-cell infection with a SIV mutant related to altered humoral immune responses

Experimental Protocol


A SIV mutation (SIVmac239 Nef G63E) found to be enriched in rhesus monkeys with enhanced SIV-specific antibody responses was reconstituted on a pBR-based SIV molecular clone pBRmac239. HSC-F cynomolgus macaque central memory Th2-like T cells were infected with mutant and wild type SIVmac239 at MOI 5 in triplicate along with uninfected controls (i.e. a total of 9 samples) for 24 hours and subjected to analysis of their gene expression patterns.

Repositories


GEO

GSE65806

ArrayExpress

E-GEOD-65806

BioProject

PRJNA275117

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