|Application:||Gene expression microarray analysis|
|Number of samples:||9|
|Release date:||Jan 1 2016|
|Last update date:||Aug 22 2018|
|Dataset link||Gene expression profile in CD4+ T-cell infection with a SIV mutant related to altered humoral immune responses|
A SIV mutation (SIVmac239 Nef G63E) found to be enriched in rhesus monkeys with enhanced SIV-specific antibody responses was reconstituted on a pBR-based SIV molecular clone pBRmac239. HSC-F cynomolgus macaque central memory Th2-like T cells were infected with mutant and wild type SIVmac239 at MOI 5 in triplicate along with uninfected controls (i.e. a total of 9 samples) for 24 hours and subjected to analysis of their gene expression patterns.