Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 2
Release date: Jun 15 2016
Last update date: Feb 22 2018
Access: Public
Diseases: Carcinoma, Hepatocellular, Liver Neoplasms
Dataset link NUPR1 a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance

Experimental Protocol


To better understand the molecular mechanisms of NUPR1 gene action in ovarian HCC cells, we employed the Agilent Whole Human Genome microarrays, containing ~ 44,000 genes to identify global gene expression changes upon NUPR1 suppression in HCC cells. We compared the gene expression of the previously selected shRNA-mediated NURP1-knockdown Hep3B clone against the corresponding control (ctrl) clone. The microarray experiments were performed in duplicates, as two hybridizations were carried out for the NUPR1-suppressing cell clone against the corresponding control, using a fluorescent dye reversal (dye-swap) technique.

Repositories


GEO

GSE73521

ArrayExpress

E-GEOD-73521

BioProject

PRJNA297209

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Contact


Dimcho Bachvarov

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