|Number of samples:||14|
|Release date:||Nov 16 2015|
|Last update date:||Oct 17 2018|
|Computational protocol:||DESeq2, FourCSeq|
|Dataset link||Multiplexed analysis of chromosome conformation at vastly improved sensitivity|
NG Capture-C combines 3C library preparation with oligonucleotide capture for the desired viewpoint restriction fragments, in this case the promoters of genes were exclusively used. The capture step has been optimised to markedly increase the sensitivity of the method (by introducing a double capture step), providing unprecedented levels of sensitivity and reliability for high resolution analysis of the chromatin landscape.
DOI: 10.1038/nmeth.3664call_split See protocol