Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 33
Release date: Mar 1 2017
Last update date: Aug 23 2018
Access: Public
Diseases: Medulloblastoma, Neoplasms
Dataset link Pten deletion in neonatal brain induces an abnormal neural progenitor niche that can synergize with Trp53 loss to generate medulloblastoma

Experimental Protocol


Copy number changes of this Medulloblastoma model was investigated using aCGH for 18 tumors. Gene expression profiling was done using Affymetrix HG-U133 plus 2 arrays for 6 tumors, 3 mouse brain with Pten wildtype at P5, 3 mouse brain with Pten null at P5, 3 mouse brain at adult age. The double knockout mouse are mixed background of FVB and C57BL/6.

Repositories


GEO

GSE40106

BioProject

PRJNA173366

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Contact


David Finkelstein