Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 18
Release date: Apr 25 2014
Last update date: Jun 14 2018
Access: Public
Dataset link SIRT1 but not its increased expression is essential for lifespan extension in caloric restricted mice.

Experimental Protocol


2-5 month old male mice of 3 different genotypes (SIRT1+/+, SIRT1+/-, and SIRT1-/-) that had normal, reduced or no expression of SIRT1 were treated with either a 40% caloric restricted diet (CR) or an ad libitum diet (AL). 2-4 replicates of each experimental condition were used in the analysis.

Repositories


GEO

GSE46895

ArrayExpress

E-GEOD-46895

BioProject

PRJNA202976

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Contact


Kevin Becker
Kevin G Becker

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