|Application:||Gene expression microarray analysis|
|Number of samples:||23|
|Release date:||Apr 27 2018|
|Last update date:||Jul 30 2018|
|Chemicals:||Bile Acids and Salts|
|Dataset link||Transcriptomic Analysis of Hepatic Cells in Multicellular Organotypic Liver Models|
We measured gene expression in hepatocytes, LSECs, and Kupffer cells from the 3DHL and 3DHLK models at day 12 to better understand LSEC function in in vitro liver cultures. For additional comparisons, we collected gene expression from hepatocytes in a collagen sandwich (CS) and hepatocyte monolayer (HM) as well as Kupffer cells at day 3 prior to their inclusion in the 3D liver model. We obtained Affymetrix microarray data for 23 samples, considering three cell-types and across four culture systems. Each cell-type culture system was performed in triplicate, except Kupffer cells at day 12 was performed in duplicate.
T. M. Murali