|Number of samples:||160|
|Release date:||Oct 30 2017|
|Last update date:||Nov 21 2018|
|Chemicals:||Kynurenine, Quinolinic Acid|
|Dataset link||RNAseq data on single dose KMO inhibitor (CHDI-00340246) treated R6/2 mice.|
12 wk old R6/2 and WT mice were treated per os with a single dose of 10 mg/kg CHDI-00340246 or vehicle (10% (w/v) HP-β-CD in 50mM Citrate Buffer (pH 5.5)); striatum, cortex, cerebellum and liver tissues were collected 6 hrs following administration. N = 10 per group (5M/5F).