Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 160
Release date: Oct 30 2017
Last update date: Nov 21 2018
Access: Public
Diseases: Huntington Disease
Chemicals: Kynurenine, Quinolinic Acid
Dataset link RNAseq data on single dose KMO inhibitor (CHDI-00340246) treated R6/2 mice.

Experimental Protocol


12 wk old R6/2 and WT mice were treated per os with a single dose of 10 mg/kg CHDI-00340246 or vehicle (10% (w/v) HP-β-CD in 50mM Citrate Buffer (pH 5.5)); striatum, cortex, cerebellum and liver tissues were collected 6 hrs following administration. N = 10 per group (5M/5F).

Repositories


GEO

GSE106161

ENA

SRP121465

BioProject

PRJNA415795

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Contact


Jeff Aaronson