|Application:||Gene expression microarray analysis|
|Number of samples:||3|
|Release date:||Oct 11 2011|
|Last update date:||Oct 2 2015|
|Chemicals:||Amino Acids, Steroids|
|Dataset link||Expression data from Xenopus laevis liver|
We used microarrays to detect global transcriptional changes in Xenopus laevis livers following pregnenolone and artemisinin treatment in order to identify target genes of xlCAR. Arteminisin or pregnenolone were injected intraperitoneally into three frogs on two consecutive days. The control group received in parallel two DMSO injections. All frogs were sacrificed 24 h after the second injection by decapitation, and livers were immediately frozen in liquid nitrogen. After RNA isolation, specimens within the same experimental group were pooled.