Computational protocol: BARD1 serum autoantibodies for the detection of lung cancer

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Protocol publication

[…] To achieve efficient discrimination between cancer and control patients, we performed logistic regression analysis using the Lasso (least absolute shrinkage and selection operator) method [–]. All computations and analyses were performed using the R software. The glmnet package [] was used for fitting lasso logistic regression, and the ROCR [] and OptimalCutpoints [] packages were used for generating and analyzing ROC curves. […]

Pipeline specifications

Software tools Lasso, ROCR, OptimalCutpoints
Applications Miscellaneous, Medical phenotype analysis
Organisms Homo sapiens
Diseases Lung Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome