Computational protocol: Molecular Typing and Epidemiology Profiles of Human Adenovirus Infection among Paediatric Patients with Severe Acute Respiratory Infection in China

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Protocol publication

[…] The partial hexon gene sequences have been deposited in GenBank under the accession numbers KM377987-KM378038 and KM877524-KM877547. A total of 28 prototype reference sequences of HAdV used for comparisons with sequences from this study were obtained from GenBank (). These were aligned and manually adjusted using Clustal X2 and BioEdit. The phylogenetic tree was drawn based on the hexon region of adenovirus by the neighbour-joining (NJ) method using Molecular Evolutionary Genetics Analysis (MEGA) software version 5.0. […]

Pipeline specifications

Software tools Clustal W, BioEdit, MEGA
Application Phylogenetics
Organisms Homo sapiens, Human mastadenovirus B, Human mastadenovirus C, Viruses
Diseases Adenoviridae Infections, Infection, Severe Acute Respiratory Syndrome, Coinfection