Computational protocol: Soft Tissue Artefacts of the Human Back: Comparison of the Sagittal Curvature of the Spine Measured Using Skin Markers and an Open Upright MRI

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Protocol publication

[…] Seven healthy subjects (three female; average age 29 y (range 22–46); height 174 cm (160–184); mass 71 kg (55–96)) provided written informed consent to participate in this pilot study that was approved by the local ethics committee. Subject recruitment was achieved through voluntary participation after public poster advertising. The participant on has seen this manuscript and figure and has provided written informed consent for its use in publication. A wide range of subject height and weight was chosen in order to exemplarily investigate the range of kinematics that could be observed within a broad population. A power analysis (one-tailed paired t-test, α = 0.05, β = 0.1) performed using a statistical software package (G*Power 3.1.3) , based on the determined accuracy of the acrylic plate measuring system (SD of the curvature angle due to the measurement system: 3.6°) and one test measurement (difference in lumbar curvature angle between the upright and extended position: 8°) with an effect size dz of 1.571 (where ) revealed a minimum subject number of six with a power level of 0.948. [...] All statistics were determined using IBM SPSS Statistics (v19, SPSS Inc., Chicago, USA). Statistical significance was defined as p<0.05. The absolute marker artefact was analysed using analyses of variance (ANOVA) for the subjects, positions and marker locations. Furthermore, correlations between the curvature angles based on the marker and vertebral body coordinates were investigated using linear regression analysis. […]

Pipeline specifications

Software tools G*Power, SPSS
Application Miscellaneous
Organisms Homo sapiens