Computational protocol: Exploration of small RNA-seq data for small non-coding RNAs in Human Colorectal Cancer

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Protocol publication

[…] To investigate biological pathway interactions of small RNA expression, we used MetaCore pathway analysis of differentially expressed genes (Thomson Reuters, New York, NY) , , to delineate functional gene networks. This was based on differentially regulated gene lists with p<0.05 from each group (tumor vs benign, metastasis vs benign, metastasis vs tumor) as input (Data analyzed by Gene Arrays, New York, USA) to generate disease biomarkers and GO terms. […]

Pipeline specifications

Software tools MetaCore, FGNet
Application Gene expression microarray analysis
Organisms Homo sapiens