|Application:||Gene expression microarray analysis|
|Number of samples:||6|
|Release date:||Apr 27 2017|
|Last update date:||Mar 6 2018|
|Diseases:||Leukemia, Leukemia, Myeloid, Acute|
|Dataset link||MicroRNA-155 is upregulated in Hoxa9/Meis1 leukemia inducing cells but is dispensable for in vivo transformation and leukemia development|
Murine bone marrow cells with or without miR-155 knocked out were transduced with Hoxa9-GFP + Meis1-YFP vectors and harvest for mRNA expression array. Three independent experiments were performed for each of the different conditions included in the study. Cells from were also transplanted into lethally irradiated mice to test for their transforming and leukemic potential.