Computational protocol: Optical Intensities of Different Compartments of Subretinal Fluid in Acute Vogt-Koyanagi-Harada Disease

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Protocol publication

[…] The software SPSS (version 17.0; SPSS, Inc., Chicago, IL) was used to conduct statistical analysis. The intraclass correlation coefficients (ICC) were determined by a two-way mixed effects model for measurements of absolute agreement. The optical intensity is affected by many factors, such as OCT signal strength and media opacity. We calculated the optical intensity ratio of the subretinal space divided by the vitreous humour [, ]or the entire scanned region [] for normalization. The optical intensity ratio of the supra-septa or sub-septa space in VKH eyes with subretinal septa was compared to that of the subretinal space in VKH eyes without subretinal septa and CSCR eyes by one-way analysis of variance and the Student-Newman-Keuls test. The optical intensities of sub-septa and supra-septa space in the same eyes were compared by a paired t-test because they were affected by the same level of signal strength or media opacity. Pearson correlation between optical intensity ratios and the best-corrected visual acuity at presentation or at the last follow-up was assessed. P values of less than 0.05 were considered statistically significant. SPSS (version 22.0, IBM Inc. Chicago, IL) software was used to perform statistical analysis and Sigmaplot (version 12.0, Systat Inc. Chicago, IL) software was used to draw statistical plots. […]

Pipeline specifications

Software tools SPSS, SigmaPlot
Application Miscellaneous
Diseases Uveomeningoencephalitic Syndrome