Dataset features

Specifications


Dataset type: Expression profiling by high throughput sequencing, Other
Number of samples: 18
Release date: Jan 28 2019
Last update date: Feb 8 2019
Access: Public
Dataset link EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC

Experimental Protocol


Comparison of Ribosome footprints in the context of EIF1AX-splice mutated (C643) and splice reverted isogenic cell line (C643-spl- rev), three replicates of ribosome-protected RNA sequencing and three replicates of RNA-seq were used. Additionally, 3 replicates of RNA-seq comparing KRAS G12R mutant CAL62 vs. CAL62-splice, an isogenic cell line generated with CRISPR-Cas9 mediated knock in of EIF1AX-splice mutation.

Repositories


GEO

GSE113695

ENA

SRP142722

BioProject

PRJNA453686

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Contact


James Fagin