Two-dimensional gel electrophoresis image analysis software tools | Mass spectrometry-based untargeted proteomics
Image analysis of two-dimensional gel electrophoresis is a key step in proteomic workflow for identifying proteins that change under different experimental conditions. Since there are usually large amount of proteins and variations shown in the gel images, the use of software for analysis of 2D gel images is inevitable.
A software tool to analyze gel or blot features, capture optimized image data, and generate a comprehensive report in just a few seconds. The main functions include single integrated and automated workflow, detailed tutorials and a security edition available for compliance with US FDA 21 CFR Part 11 regulations.
Allows 2-D gel electrophoresis analysis. PDQuest 2-D is an analysis software available in basic or advanced version. The software PDQuest controls the imaging systems, collects and manages large amounts of image data, and analyses the information. It uses automated spot-matching algorithm, normalisation between gel images, statistical and qualitative query reports and also merging of multiple images in the same gel.
Enables construction, manipulation, analysis and comparison of mass spectrometry (MS) images. MSight is designed for 2-D representation, as well as visual analysis and comparison of datasets obtained from protein or peptide separation combined to MS. The software allows navigation through large volumes of data and provides visualization tools to discriminate peptide or protein from noise or to perform differential analysis. It aims to improve understanding of correlated high-throughput MS.