Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 10
Release date: Sep 18 2018
Last update date: Sep 19 2018
Access: Public
Diseases: Heart Failure
Genes: ING4, Grk2, AC4, GRK2, PEBP1, QR1, Chrp
Mutations: p|SUB|K|220|R
Taxon: Homo sapiens, Mus musculus
Dataset link Whole genome cardiac gene expression profiling of transgenic mice with myocardium-specific expression of RKIP (PEBP1), kinase-inactive GRK2-K220R (ADRBK1-K220R), SCD1, and UCP1

Experimental Protocol


Whole genome microarray gene expression profiling was performed of hearts from aged, 8-month-old Tg-RKIP mice, Tg-GRK2-K220R mice, Tg-SCD1 mice, and Tg-UCP1 mice. All transgenic mice had B6 background, and the control group consisted of age-matched non-transgenic B6 mice. Two biological replicates were made of each group, and total cardiac RNA of three mice was pooled for one gene chip.

Repositories


GEO

GSE120020

BioProject

PRJNA491406

Download


Contact


Ursula Quitterer