Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 40
Release date: Oct 12 2012
Last update date: Aug 9 2018
Access: Public
Diseases: Lymphoma, Follicular, Lymphoma, B-Cell
Dataset link Gene expression profiling of EZH2 mutant and wild type DLBCL cell lines treated with EZH2 inhibitor

Experimental Protocol


10 DLBCL cell lines (7 mutant and 3 wild type EZH2), that were differentially sensitive to GSK126 in proliferation assays, were treated for 72 hours, in duplicate (n=2), with either DMSO (vehicle) or 500nM of GSK126, a potent selective EZH2 inhibitor. EZH2 mutant cell lines are Pfeiffer, KARPAS-422, WSU-DLCL2, SU-DHL-10, SU-DHL-6, DB and SU-DHL-4. EZH2 wildtype cell lines are HT, OCI-LY-19 and Toledo.

Repositories


GEO

GSE40971

ArrayExpress

E-GEOD-40971

BioProject

PRJNA175452

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Contact


Gopinath Ganji