Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 4
Release date: Jul 30 2014
Last update date: Aug 23 2018
Access: Public
Diseases: Leukemia, Neoplastic Syndromes, Hereditary, Leukemia, Myeloid, Acute
Chemicals: Nucleotides
Dataset link Association of prognosis of acute myeloid leukemia patients with leukemia stem cell gene signature based on nucleostemin promoter activity

Experimental Protocol


A mouse acute myeloid leukemia model was generated by introduction of HoxA9/Meis1 to bone marrow cells from a transgenic mouse, in which green florescence protein (GFP) is expressed under the control of particular region of NS promoter (NS-GFP).The leukemia cells were fractionated into 4 subpopulations based on NS-GFP level and c-Kit expression, (a) c-Kit-NS-GFPlow, (b) c-Kit-NS-GFPmiddle, (c) c-Kit+NS-GFPmiddle and (d) c-Kit+NS-GFPhigh cells.

Repositories


GEO

GSE58032

ArrayExpress

E-GEOD-58032

BioProject

PRJNA248748

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Contact


Atsushi Hirao