|Application:||Gene expression microarray analysis|
|Number of samples:||9|
|Release date:||Feb 1 2015|
|Last update date:||Aug 9 2018|
|Dataset link||Enhancing the Functional Maturity of iPSC-Derived Human Hepatocytes Via Controlled Presentation of Cell-Cell Interactions In Vitro|
To assess the transcriptomic stability of iHeps in iMPCCs, RNA was extracted following 9 and 21 days of culture for hybridization to Affymetrix microarrays. The hepatic maturation state of iHeps was assessed by comparing gene expression against microarrays containing data from two primary human hepatocyte donors, both following hepatocyte isolation (day 0) and after stabilization in the micropatterened co-culture platform (day 6 and day 42 MPCCs), as previously described.