Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 8
Release date: Jun 3 2014
Last update date: Aug 10 2018
Access: Public
Diseases: Breast Neoplasms, Neoplasms
Chemicals: Estrogens
Dataset link Novel Roles for ERK5 and Cofiin as Critical Mediators Linking Estrogen Receptor α-Driven Transcription, Actin Reorganization and Invasiveness in Breast cancer

Experimental Protocol


MCF-7 human breast adenocarcinoma cells were tranfected with control, and ERK5 siRNA for 72 hours and treated with 0.1% EtOH (Vehicle) or 10 nM E2 for 24 hours, and cDNA microarray analyses were carried out using Affymetrix [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array. siRNA knock-down, ligand treatment

Repositories


GEO

GSE53394

ArrayExpress

E-GEOD-53394

BioProject

PRJNA231915

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