Dataset features

Specifications


Dataset type: Expression profiling by array
Number of samples: 24
Release date: Dec 17 2018
Last update date: Dec 18 2018
Access: Public
Dataset link Expression data from hearts (left ventricle apex) of rats with and without metformin treatment

Experimental Protocol


Male RccHan Wistar rats at the age of 7-8 weeks were randomly assigned to the vehicle or treatment group (n=5). Then 0 or 800 mg/kg metformin (Sigma Aldrich, Steinheim, Germany) was administered by gavage for 1, 3 or 14 consecutive days, followed by necropsy. Blood was collected for for lactate determination and several organs were removed, weighted, aliquoted, fixed in formalin for histopathological examinations or flash frozen in liquid nitrogen and stored at −80 °C for RNA isolation.

Repositories


GEO

GSE122604

BioProject

PRJNA505707

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Contact


Heidrun Ellinger-Ziegelbauer