|Application:||Gene expression microarray analysis|
|Number of samples:||59|
|Release date:||Oct 1 2015|
|Last update date:||Feb 2 2018|
|Dataset link||Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to benzo(b)fluoranthene in lung, liver, and forestomach tissues [BbF]|
This experiment examined the pulmonary, hepatic, and forestomach transcriptional response of male mice exposed to benz(a)anthracene for 28 days at three different doses, including D1 (25 mg/kg-bw/day), D2 (50 mg/kg-bw/day), and D3 (100 mg/kg-bw/day) and vehicle control (D0). Each dose group was examined 72 hours following the final exposure. Each dose group had 4-5 biological replicates. There were a total 19, 20, and 20 samples (arrays) from the lung, liver, and forestomach, respectively, included in the final analysis using a two-colour reference design.
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Archives of Toxicology