Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 15
Release date: Oct 6 2007
Last update date: Aug 28 2018
Access: Public
Diseases: Osteosarcoma
Chemicals: Glutathione, Sorbitol, Valproic Acid
Dataset link Effect of histone deacetylase inhibitors on osteoblast gene expression

Experimental Protocol


To identify other osteoblast genes that are altered early by HDIs, we incubated MC3T3-E1 preosteoblasts with HDIs (trichostatin A, MS-275, or valproic acid) or the vehicle control (DMSO) for 18 hours in osteogenic conditions. Gene expression profiles relative to vehicle-treated cells were assessed in triplicate (in some cases quadruplicate) samples by microarray analysis with Affymetrix GeneChip 430 2.0 arrays.

Repositories


GEO

GSE9247

ArrayExpress

E-GEOD-9247

BioProject

PRJNA102859

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