Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 6
Release date: Feb 16 2018
Last update date: Nov 27 2018
Access: Public
Diseases: Carcinoma, Hepatocellular, Liver Diseases
Genes: ALK2, KMT2A
Dataset link Transcriptome profiling of HepG2 cells upon treatment of the menin-MLL inhibitor MI-503 or DMSO

Experimental Protocol


HepG2 cells were plated in the 12-well plates at the initial concentration of 0.4x106 cells/ml and treated with 3 μM MI-503 or DMSO (0.25%) in triplicates. After 3 days of treatment viable cell number was adjusted to the original concentration in the DMSO treated samples and the same dilution factor was used to adjust cell number in the MI-503 treated cells. Media was changed and compound or DMSO was re-supplied at that time. Cells were harvested after 3 more days of incubation.

Repositories


GEO

GSE103327

ENA

SRP131324

BioProject

PRJNA401703

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Contact


Jingya Wang