Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 40
Release date: Dec 1 2015
Last update date: Oct 24 2018
Access: Public
Genes: PRDM1, IRF4, IGH, IGK, ELL2
Dataset link Multifunctional role of the transcription factor Blimp1 in coordinating plasma cell differentiation

Experimental Protocol


40 samples in total: A) 16 RNA-Seq samples in 5 cell types: Activated B cells (Act B cell, 2 replicates), Pre-Plasmablasts (Pre-PB, 3 genotypes, 2-4 replicates each), Plasmablasts (PB, 2 replicates), Plasma cells (2 replicates), Mature B cells (2 replicates); B) 19 ChIP-Seq samples in 3 cell types: Act B cell (IRF4, H3K9ac, H3K4me2, H3K4me3, 1 replicate each; H3K27me3, 2 genotypes, 2 and 1 replicates), Pre-PB (IRF4, 1 replicate; H3K27me3, 2 genotypes, 1 replicate each), PB ( PU.1, IRF4, H3K9ac, H3K4me2, H3K4me3, 1 replicate each; Blimp1, H3K27me3, 2 replicates each); C) 5 ATAC-Seq samples in 3 cell types: Act B cell (2 genotypes, 1 replicate each), Pre-PB (2 genotypes, 1 replicate each), PB (1 replicate).

Repositories


GEO

GSE71698

ENA

SRP061982

BioProject

PRJNA291849

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Contact


Markus Jaritz