Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 530
Release date: Jul 24 2018
Last update date: Jul 26 2018
Access: Public
Genes: GRN
Taxon: Plum pox virus
Dataset link Gene expression profiling of subclinical acute kidney rejection I

Experimental Protocol


307 KTR were enrolled into a multi-center observational study. Precise clinical phenotypes (CP) were used to define subAR. Differential gene expression (DGE) data from peripheral blood samples paired with surveillance biopsies were used to train a Random Forests (RF) model to develop a gene expression profile (GEP) for subAR. A separate cohort of paired samples was used to validate the GEP. Clinical endpoints and gene pathway mapping were used to assess clinical validity and biologic relevance.

Repositories


GEO

GSE107503

BioProject

PRJNA420420

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Contact


Sunil Kurian