Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 25
Release date: Oct 10 2016
Last update date: Oct 24 2018
Access: Public
Diseases: Amnesia, Arthritis, Rheumatoid, Encephalomyelitis, Autoimmune, Experimental, Multiple Sclerosis, Myositis, Superinfection, Inflammatory Bowel Diseases, Malaria, Cerebral
Dataset link USP15 regulates type I interferon response in vivo and is required for pathogenesis of microbial and autoimmune neuroinflammation

Experimental Protocol


Sequencing of RNA extracted from target tissue in two experimental neuroinflammation models in wild-type (B6), USP15(L749R) and Trim25 KO mutant mice: (1) brains at day 3 and 5 following Plasmodium berghei ANKA (PbA) infection for the cerebral malaria model (ECM); and (2) spinal cords at day 7 following induction of experimental autoimmune encephalomyelitis (EAE) for B6 and Usp15 mutant mice only.

Repositories


GEO

GSE79702

ENA

SRP072526

BioProject

PRJNA316741

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Contact


David Langlais