|Application:||Gene expression microarray analysis|
|Number of samples:||6|
|Release date:||Jun 1 2013|
|Last update date:||Aug 9 2018|
|Taxon:||Homo sapiens, Rattus norvegicus|
|Dataset link||Temporal induction of immunoregulatory processes coincides with age-dependent resistance to viral-induced type 1 diabetes [human]|
Fresh PBMCs of a healthy control donor were isolated by density gradient centrifugation. These cells were then stimulated with 20% plasma from a longitudinally monitored sibling of a T1D patient that progressed to T1D (n= 6 timepoints) at 37C in 5% CO2. Gene expression analysis was perfromed in order to evaluate the transcriptional signature associated with T1D pathogenesis.
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