Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 11
Release date: Jul 6 2017
Last update date: Nov 19 2018
Access: Public
Diseases: Alzheimer Disease
Mutations: p|SUB|K|670|N, p|SUB|M|671|L
Dataset link Identification of downstream genes regulated by YAP1 through knockdown and overexpression of YAP1 in U251 cell with a stably expression of mutant APP

Experimental Protocol


YAP1 inteference and overexpression were performed in U251 cell with a stably expression of mutant APP (K670N/M671L) (U251-APP cells) with three biological triplicates for each condition (siNC, si-YAP1, vector, and YAP1, one outlier for YAP1 overexpression was removed). Differential expression genes were obtained by comparing gene expression levels in YAP1 knockdown (si-YAP1) or overexpression (YAP1) cells with control cells (siNC or vector).

Repositories


GEO

GSE100891

ENA

SRP111293

BioProject

PRJNA393355

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Contact


Yong-Gang Yao